Adaptogens are the plant-derived biologically active substances that appear to induce a state of non-specific increase of resistance of the organism to diverse assaults that threaten internal homeostasis and improve physical endurance.1Supplementation with various macro and micronutrients and herbal preparations has been evaluated for their adaptogenic activity during exposure to a stressful environment.2 Stress research in laboratory animals has assumed an important role in understanding the biological and behavioral consequences of external or internal stressors, which threaten to perturb homeostatis and may induce a number of clinical diseases when the body fails to counteract the stress situations. A variety of stress situations have been employed to investigate the consequences of stress and to evaluate antistress agents. The pharmacological assessment of adaptogens typically includes evaluation of their stimulating, tonic and stress protective effects in different screening models in which animals are challenged to acute and chronic stress conditions. Stress mediators and biochemical markers involved in mechanism ofadaptogens may be evaluated using experimental procedures.3
: 0 | PDF
Copyright (c) 2014 International Journal of Biomedical Research
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- An author must submit Copyright form After acceptance of the article.